After a lengthy wait, season 2 of Natsu Hyuga's hit series is finally returning this January, and season 2 promises just as much excitement as the first.
Toho Animation recently shared a new full-length trailer for season 2 of The Apothecary Diaries releasing on January 10, 2025. The new trailer teases the many intriguing plot points that will be explored in season 2, with the main highlight being an adorable interaction between Jinshi and Maomao wherein the latter responds to Jinshi without a hint of her usual exasperation for once. Besides these teasing glimpses, the new trailer also features a snippet of the new opening theme for season two titled "Hyakka Ryoran" performed by Lilas Ikuta, the vocalist of the famed duo, YOASOBI.
The Apothecary Diaries’ New Season 2 Trailer Teases a Huge Improvement in Jinshi and Maomao’s Relationship
Jinshi and Maomao May Finally Be Taking a Step Forward
The new trailer starts off with Jinshi sharing some floor plans with Maomao. Leaving behind her usual snark and sarcasm, Maomao uncharacteristically replies with an earnest smile, ive of Jinshi's idea, which is to build an institute to teach the court ladies and their ladies-in-waiting to read and write, which is expected to be one of the many plot points in season 2.
Though small, this wholesome interaction in the latest season 2 trailer showcases just how far Jinshi and Maomao's relationship has progressed since the beginning of season 1. With romance being a subplot for the most part, the relationship between the two has progressed at a snail's pace with Maomao's feelings regarding Jinshi still remaining ambivalent as best. Nonetheless, season 2 of The Apothecary Diaries will likely see Jinshi and Maomao get even closer, especially now that Maomao has discovered at least some things that she likes about Jinshi.
Plenty of New Mysteries Await in Season 2 of The Apothecary Diaries
Besides the surprising interaction between Jinshi and Maomao, the new trailer for season 2 also introduced many exciting new characters, such as Shisui (voiced by Asami Seto), a new servant girl who seems to be just as ionate about bugs and insects as Maomao is about herbs and poisons. The trailer also gives fans a glimpse of "onisher of Thieves", an adorable new kitten set to the inner court and steal viewers' hearts in season 2.
Season 2 of The Apothecary Diaries is also expected to be chock-full of intriguing medical mysteries, with the newest trailer teasing many of these intertwining plots. From a curious smell in a certain area of the court to the infiltration of new poisons and a new plot to harm one of the consorts, season 2 is already shaping up to be quite a thrilling adventure.
Don't miss season 2 of The Apothecary Diaries when it releases on January 10, 2025!
Source: Toho Animation/YouTube

The Apothecary Diaries
- Release Date
- October 22, 2023
- Network
- Nippon TV, RAB, TVI, YBC, JRT
- Directors
- Jun Owada, Akira Koremoto, Kentaro Fujita, Yukihiko Asaki, Erkin Kawabata, Shintaro Itoga, Tsuyoshi Nakano, Akira Shimizu, Yuushi Ibe, Kyohei Yamamoto, Masahiro Matsunaga, Tadao Okubo, Misu Yamaneko
Cast
- Aoi YukiMaomao (voice)
- Takeo OtsukaJinshi (voice)
The Apothecary Diaries follows Maomao, sold from her peaceful life to serve in the emperor’s palace. Her unique talents emerge when she solves a medical crisis involving the imperial heirs, attracting the attention of Jinshi, a palace official, and launching her into the complex world of palace intrigue and mysteries.
- Writers
- Yuko Kakihara, Misuzu Chiba, Hitomi Ogawa
- Creator(s)
- Natsu Hyūga
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