Don't Look Up follows two astronomers (Leonardo DiCaprio and Jennifer Lawrence) desperately trying to warn humanity about an approaching comet that they believe could wipe out all life on Earth. When the President (Meryl Streep) and her son (Jonah Hill) ignore their warnings, they embark on a media tour to enlighten the public, earning the ire of the global populace who refuse to believe in the danger. Meanwhile, an eccentric billionaire (Mark Rylance) begins to fund an emergency colonization mission to take humanity out among the stars.