the best episodes of House featured the team in continuous debate about what constituted the ethical choice. House was loosely based on Sherlock Holmes, which is why it was one of the first modern medical shows to introduce to inject mystery and deductive logic into the genre.

If you’re a fan of House, you might want to check out some of these more recent medical shows, including some of anyone who misses House. Many of these TV series are inspired by House, building on its legacy and even taking some of the elements fans loved further.

10 St. Denis Medical (2024-Present)

This Medical Mockumentary Shows The Humor In Practicing Medicine

Though House is a medical drama, it often leaned into dark comedy, making it nearly a dramedy. St. Denis Medical is NBC’s more lighthearted sitcom, but both shows acknowledge that medicine isn’t just about life-or-death decisions, it’s about the absurd, the frustrating, and the deeply human moments that happen in hospitals.

While House focused on one brilliant but misanthropic doctor solving medical puzzles, St. Denis Medical embraces an ensemble of well-meaning but flawed doctors and nurses, showcasing the daily chaos with a lighter touch. Both series remind audiences that even in serious professions, humor is essential, whether it’s House’s biting sarcasm or St. Denis Medical’s workplace antics. St. Denis’s renewal for season 2 proves audiences still love seeing the lighter, chaotic side of healthcare.

9 Doc (2025-Present)

Dr. Amy Larsen Is A Brilliant Diagnostician With A Brutal Bedside Manner

Fox's new series Doc has a lot in common with House, particularly in its medical approach and the character of Dr. Amy Larsen, at least before her accident, who comes across as a more abrasive version of herself. Both Amy and House exhibit a relentless drive to solve complex medical cases, often believing they know best and breaking the rules ostensibly for the sake of their patients, although also to boost their own egos.

Like House, Amy is unorthodox, blunt, and determined, willing to go to extreme lengths to uncover the truth.

Like House, Amy is unorthodox, blunt, and determined, willing to go to extreme lengths to uncover the truth. While House followed a more structured case-of-the-week format, Doc leans into an overarching mystery with emotional and romantic entanglements. Fans of House will appreciate Doc’s difficult medical decisions, emotional complexity, and Amy’s uncompromising commitment to her patients. Doc's season 1 finale has a lot of unanswered questions that will hopefully be addressed in season 2.

8 The Good Doctor (2017-2024)

A More Humanistic Approach To A Doctor Who Sees Things Differently

The Good Doctor and House both centered on brilliant medical minds who struggled with social norms but ultimately improved patient outcomes because of their unique perspectives. Freddie Highmore’s Dr. Shaun Murphy, whose autism creates a communication barrier, often makes unintentional missteps, while House’s prickly demeanor is more of a conscious choice. David Shore, the creator of House, also created this show, so it’s no surprise it explores similar territory and had a successful run, with 126 episodes over The Good Doctor's seven seasons.

In some ways, The Good Doctor was almost an emotional inverse of House: Shaun is kind-hearted and trying his best, but still makes social faux pas, while House is jaded and often intentionally difficult. Yet both challenged the medical system, had a gift so special exceptions were made for them, and solved cases no one else could. Their brilliance lay in how they thought differently, and both shows explore the tension between being right and being understood.

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7 Mary Kills People (2017-2019)

An ER Doctor By Day Provides Assisted Suicides At Night

Mary Kills People shared key thematic ground with House, especially in its exploration of morally gray areas in medicine. Dr. Mary Harris was an ER doctor by day and an underground provider of assisted suicides by night, an act that was illegal but rooted in comion and patient autonomy. House, with his deep disdain for bureaucracy and reverence for logic over rules, would likely approve of Mary’s rebellion.

Mary Kills People has a 100% rating on Rotten Tomatoes.

Both characters prioritize what they believe is right over what is legal or expected, often at great personal risk. This Canadian series, with just 18 episodes, delivers a sharp, ethically complex story about the limits of medical care, the weight of choice, and the humanity behind tough decisions, very much in House’s wheelhouse.

6 New Amsterdam (2018-2023)

Dr. Max Wants To Tear Down Hospital Bureaucracy To Provide Better Care

New Amsterdam and House both took a critical look at the flaws in the medical system, though from different angles. Dr. Max Goodwin, like House, was willing to break rules to prioritize patient care, but while House did so out of intellectual defiance, Max was driven by optimism and a desire to fix a broken system, based on the true story of Eric Manheimer. Dr. Goodwin’s approach of eliminating bureaucracy and putting patients first mirrored House’s belief that red tape often gets in the way of real medicine.

While New Amsterdam had a more hopeful, emotionally uplifting tone, it still scratches the same itch for viewers who enjoy medical dramas that challenge hospital norms. With five seasons, New Amsterdam delivered a more heartfelt but equally rebellious take on reforming healthcare.

5 The Pitt (2025-Present)

If You Liked The Diagnostic Procedures In House, The Pitt Ups The Medical Gore

The Pitt doubles down on realism, capturing the chaotic and relentless pace of an emergency room.

Its real-time storytelling style, reminiscent of 24, also calls to mind House’s special episodes that broke format, like "5 to 9", which followed Dr. Cuddy’s nonstop day running the hospital. By immersing viewers in the intense, moment-to-moment challenges faced by medical professionals, The Pitt offers a gripping, authentic, and immersive experience that mirrors House’s commitment to showing the highs and lows of medicine. Season 1 is still airing, and the show has already been a huge hit for Max, which has renewed The Pitt for season 2.

4 Pure Genius (2016-2017)

A Maverick Surgeon Partners With A Silicon Valley Billionaire To Fast Track Medical Advancements

Pure Genius shared House’s fascination with medical innovation and pushing the boundaries of what’s possible in healthcare. In Pure Genius, a billionaire tech visionary and maverick surgeon partnered to challenge the traditional medical system, clearing bureaucratic obstacles to prioritize patient care. While House focused on diagnostics, Pure Genius leaned into futuristic medicine, using cutting-edge technology that does not yet exist.

Both shows balanced melodrama with humor, with Pure Genius embracing a sci-fi edge where House relied on cynical realism. Though the show only lasted one season, its bold vision and commitment to medical problem-solving make it worth checking out, especially for House fans who enjoyed watching brilliant minds defy convention to save lives.

3 The Resident (2018-2023)

Matt Czuchry’s Dr. Conrad Hawkins Breaks Rules To Help Patients Like House

If you rooted for House when he pushed boundaries for the sake of his patients, you’ll appreciate The Resident. Matt Czuchry’s Dr. Conrad Hawkins was a ionate and rebellious doctor who often challenged hospital protocol and authority to ensure the best care for his patients, regardless of the consequences. Like House, Dr. Hawkins frequently clashed with the hospital's corporate interests and bureaucratic obstacles.

The Resident balanced its intense medical drama with plenty of romantic tension and relationship dynamics, making it a great choice for viewers who enjoy both emotional depth and steamy love stories like Chase and Cameron’s relationship in House. For 107 episodes over six seasons, the doctors in The Resident fought for what’s right, even when it meant defying the system while navigating their personal lives in an engaging mix of drama and romance.

2 Transplant (2020-2024)

A Refugee Starts Over From The Bottom As A Resident

Transplant and House were both grounded medical dramas that highlight the brilliance and resilience of unconventional doctors. While House followed a prickly, rule-breaking genius, Transplant centered on Dr. Bashir “Bash” Hamed, a deeply empathetic Syrian refugee rebuilding his medical career from the ground up. Bash’s journey offered a more emotionally resonant, humanistic tone than House, but both series share a focus on complex cases, ethical dilemmas, and characters who challenge the status quo.

This Canadian series ran for four seasons and is a strong pick for fans of emotionally rich, character-driven medical storytelling with a sharp procedural core.

Bash’s background brought fresh perspective and urgency to patient care, much like House’s relentless pursuit of truth. This Canadian series ran for four seasons and is a strong pick for fans of emotionally rich, character-driven medical storytelling with a sharp procedural core.

1 Watson (2025-Present)

Watson Is More Explicitly A Sherlock Holmes Medical Mystery Adaptation Than House Was

Watson and House share clear DNA in their inspiration from Sherlock Holmes, though Watson is more overt about the connection, as Dr. John Watson is the actual former partner of Sherlock himself. Like House, Watson follows a case-of-the-week format with intriguing medical mysteries that Watson solves in brilliant, often cryptic ways, aided by a team he’s hand-selected. Both shows feature complex, emotionally guarded leads with a deep sense of justice, even if their methods are unconventional.

However, Watson adds an overarching mystery involving Watson season 2 already confirmed with season 1 still currently airing weekly.